Understanding Aciclovir Side Effects and Safety
Common Side Effects of Aciclovir
Most people taking aciclovir experience no side effects or only mild symptoms. Common side effects affecting up to 1 in 10 people include headache, dizziness, nausea, vomiting, diarrhoea, and stomach pain. These symptoms are usually mild and tend to improve as your body adjusts to the medication. Taking aciclovir with food may help reduce stomach-related side effects.
Skin Reactions and Topical Side Effects
When using aciclovir cream, some people may experience local skin reactions including mild burning, stinging, or itching at the application site. Dry or flaky skin around the treated area is also possible. These effects are typically temporary and subside once treatment is completed. If skin irritation becomes severe or spreads beyond the treatment area, discontinue use and consult your pharmacist.
Rare but Serious Side Effects
Serious side effects from aciclovir are uncommon but require immediate medical attention. These may include severe allergic reactions (difficulty breathing, swelling of face or throat), kidney problems (changes in urination, blood in urine), or neurological symptoms like confusion or tremors. Blood disorders and liver problems have been reported very rarely, particularly with high-dose or long-term treatment.
Managing Side Effects During Treatment
If you experience mild side effects, continue taking aciclovir as prescribed unless advised otherwise by your healthcare provider. Stay well-hydrated, especially when taking oral aciclovir, as this supports kidney function. For stomach upset, take tablets with food or milk. Contact your doctor if side effects persist or worsen, or if you develop any concerning symptoms.
Treatment Options Available at EverydayMeds
EverydayMeds offers comprehensive cold sore treatments including Aciclovir 400mg tablets and Aciclovir 5% cream for convenient online ordering. Alternative options like Valaciclovir 500mg tablets may be suitable if you experience side effects with aciclovir. Our online pharmacy provides easy access to antiviral treatments with discreet delivery across the UK, helping you manage outbreaks effectively whilst minimising treatment risks through proper medication guidance.






