Aciclovir Side Effects: What You Need to Know
Common Side Effects of Aciclovir Tablets
Most people tolerate aciclovir well, but some may experience mild side effects. Common reactions affect up to 1 in 10 people and typically include nausea, vomiting, diarrhoea, stomach pain, and headache. These effects are usually temporary and resolve as your body adjusts to the medication. Taking aciclovir with food may help reduce stomach-related side effects.
Serious Side Effects Requiring Medical Attention
Whilst uncommon, serious side effects can occur and require immediate medical attention. Contact your GP or call 111 if you experience severe kidney problems (reduced urination, swelling, confusion), neurological symptoms (tremors, hallucinations, seizures), or signs of liver problems (yellowing skin, dark urine, persistent nausea). These reactions are rare but need prompt medical assessment to prevent complications.
Aciclovir Cream Side Effects
Topical aciclovir cream may cause localised skin reactions at the application site. Common effects include mild burning, stinging, itching, or skin dryness. These reactions usually subside within a few days of treatment. Avoid applying cream to broken skin and wash hands thoroughly after application to prevent spreading to sensitive areas like eyes.
Allergic Reactions and Warning Signs
Severe allergic reactions to aciclovir are rare but potentially serious. Seek emergency medical help if you develop difficulty breathing, swelling of face or throat, severe skin rash, or widespread hives. Stop taking aciclovir immediately and contact healthcare services. EverydayMeds provides detailed patient information leaflets with all aciclovir products to help you identify concerning symptoms promptly.
Managing Side Effects Safely
If you experience mild side effects, continue taking aciclovir as prescribed unless advised otherwise by your healthcare provider. Stay well-hydrated, especially when taking higher doses, to support kidney function. Keep a record of any side effects to discuss with your pharmacist or GP. EverydayMeds offers both aciclovir tablets and cream with comprehensive safety information and pharmacist support for managing your treatment effectively.






